Bombing allies makes them angry...

From the Guardian via Common Dreams:

Thousands of angry protesters took to the streets across Pakistan yesterday to condemn an American air strike aimed at al-Qaida's deputy leader, Ayman al-Zawahiri, that left at least 18 people dead.

Up to 10,000 people reportedly protested at rallies in the largest city, Karachi. Many chanted: "Death to America!" Demonstrators demanded the resignation of Pakistan's president, Pervez Musharraf. Smaller protests were staged in other towns and cities, including Islamabad, Lahore, Quetta and Peshawar.

The protests across Pakistan put further pressure on General Musharraf, whose close relationship with the United States has made him unpopular at home.

...

The rallies followed violent protests by thousands of tribesmen on Saturday in the Bajaur region on the Afghan border where the attack took place. The White House has remained tight-lipped over the missile strike, said to have been carried out by the CIA on Friday, using unmanned drone aircraft.

...

Officially, the Pakistani government does not allow the 20,000 US troops in Afghanistan to cross the border in pursuit of Taliban or al-Qaida fighters, although a large number of combatants are thought to have sought refuge in the rugged and remote border region.

In recent weeks, though, there has been a string of attacks on the Pakistani side of the border that many suspect were carried out by the US. Eight people were killed in a cross-border raid last weekend.